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Hemoglobin (Hb) electrophoresis by HPLC is used to identify the different types of hemoglobin present in the blood. Hemoglobin is a protein present inside the red blood cells that functions to transport oxygen to the tissues and organs of the body. This test is done to diagnose blood disorders, as a screening test for genetic conditions, and monitor treatment efficacy in patients having blood disorders. It also detects abnormal hemoglobin types which may interfere with the oxygen flow.
  • What is haemoglobin electrophoresis?

    Haemoglobin electrophoresis is a diagnostic test that separates and identifies different types of haemoglobin in the blood. It helps determine if an individual has any abnormal haemoglobin variants or disorders.

  • Why is haemoglobin electrophoresis performed?

    Haemoglobin electrophoresis is performed to diagnose and characterize various haemoglobinopathies, such as sickle cell disease, thalassemia, and other genetic disorders affecting haemoglobin. It is also used for carrier screening and prenatal testing.

  • How is haemoglobin electrophoresis done?

    Haemoglobin electrophoresis involves collecting a small blood sample, which is then processed in the laboratory. The blood components are separated based on their electrical charge and size, and different haemoglobin variants are identified using staining or other laboratory techniques.

  • What does haemoglobin electrophoresis test for?

    Haemoglobin electrophoresis can identify normal haemoglobin (A), abnormal haemoglobin variants (e.g., S, C, D, E), as well as other variants associated with specific diseases (e.g., sickle cell trait, beta-thalassemia trait).

  • Is haemoglobin electrophoresis a painful procedure?

    No, haemoglobin electrophoresis is a relatively painless procedure. A small needle is used to collect the blood sample, which may cause a prick or slight discomfort. However, any discomfort is minimal and temporary.

  • How long does it take to get the results of haemoglobin electrophoresis?

    The time it takes to receive the results can vary from laboratory to laboratory. In some cases, results may be available within a few hours, while in others, it may take a few days.

  • Can haemoglobin electrophoresis be done on anyone?

    : Haemoglobin electrophoresis is typically performed when there is a suspicion of haemoglobin disorders or as part of routine screening in high-risk populations. It is not a routine test done on everyone.

  • Are there any risks or complications associated with haemoglobin electrophoresis?

    Haemoglobin electrophoresis is considered a safe procedure with minimal risks. The most common risk includes mild bruising or bleeding at the site where the blood sample is taken.

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