Unconjugated estriol (uE3) is a form of oestrogen (hormone) produced by the fetus (unborn baby) through metabolism. Estriol levels are used to determine birth defects and chromosomal variations in babies. Estriol is ejected from the placenta (an organ acting as the protective covering for the fetus) into the mother?s blood, and measured as unconjugated uE3. This test is mainly used for diagnosing Down syndrome. A blood sample is shared with the lab for analysis. There are no specific risks involved in taking this test, and it is considered one of the best ways to analyse an unborn baby?s health.
Estriol plays a crucial role in maintaining a healthy pregnancy and is often used as a marker for fetal well-being and placental function.
Estriol levels increase throughout pregnancy, peaking around the third trimester. Measuring estriol levels, along with other hormones such as human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP), can help assess the health of the developing fetus. Abnormal estriol levels may suggest chromosomal abnormalities or fetal distress.
Additionally, estriol has also been studied for its potential use in hormone replacement therapy (HRT) for postmenopausal women. It is considered a weaker estrogen compared to estradiol or estrone, which may provide benefits in terms of reducing the risk of certain hormone-related cancers, such as breast and endometrial cancer. However, its use in HRT requires careful consideration and individualized treatment plans.
Overall, estriol is an important hormone involved in pregnancy and the monitoring of fetal well-being. Its measurements can provide crucial information about the health of the developing fetus, while further research is being conducted to explore its potential therapeutic applications.
Report Time:
24 Hours
Fasting Time:
Free
Recommended Test:
Female
Recommended age:
5-99 Years
Book on our website or app, or request a Health Advisor callback.
Health Advisor & medical advisor provide guidance of testing process.
Enjoy free sample collection at home or office by expert phlebotomists.
Your sample is transported, processed, and verified by our expert team.
Receive AI-based Smart Reports with free consultations.