• IMMUNOGLOBULIN E (IGE) (IGE) In Jaipur

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Immunoglobulin E (IgE) is a type of antibody that plays a central role in allergic responses and immune defense against certain parasites. It is one of the five main classes of antibodies present in the bloodstream.
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Total IgE test, also known as quantitative IgE test, measures the quantity of immunoglobulin E (IgE) in the blood. When you have an allergy, your immune system regards a foreign substance, such as dust or pollen, as a threat. Your immune system fights against this threat by producing antibodies called IgE. While total IgE test measures the overall number of IgE antibodies in your blood, another type of test called a specific IgE test tells you the quantity of IgE antibodies in response to a particular allergen.

IgE is produced by plasma cells and is primarily found on the surface of specialized immune cells called mast cells and basophils. When an individual is exposed to an allergen (a substance that triggers an allergic reaction), such as pollen or certain foods, the immune system produces specific IgE antibodies directed against that allergen.

Upon subsequent exposure to the same allergen, the allergen binds to the IgE antibodies on mast cells and basophils. This binding triggers the release of chemical mediators, such as histamine, which cause allergy symptoms like itching, sneezing, skin rashes, and inflammation.

The allergic response mediated by IgE is an immune overreaction to otherwise harmless substances. It can manifest as allergic rhinitis (hay fever), bronchial asthma, atopic dermatitis (eczema), or food allergies. Elevated levels of IgE in the blood can indicate an increased risk of allergic conditions.

Apart from its role in allergic reactions, IgE also plays a protective role against parasites, particularly helminths (worms). IgE antibodies can recognize and bind to the parasites' surfaces, initiating an immune response to eliminate them.

Measurement of IgE levels in the blood can be helpful in diagnosing allergies and assessing the severity of allergic conditions. Allergy testing, such as skin prick tests or blood tests, can determine specific allergens to which an individual may be sensitized, aiding in the development of appropriate treatment plans.

In summary, Immunoglobulin E (IgE) is an antibody involved in allergic responses and immune defense against parasites. While it triggers allergic symptoms upon exposure to allergens, it also plays a protective role against certain parasitic infections. Monitoring IgE levels can aid in the diagnosis and management of allergic conditions.

IMMUNOGLOBULIN E (IGE)

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